Recommendations and contraindications

Be sure to consult your doctor before taking Tadalafil 10mg Dosage pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

• Like any other drug of this action, Tadalafil For Erectile Dysfunction is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
• The body, which is sensitive to any of the components of Cialis Tadalafil 10mg Tablets, Tadalafil Cialis 20mg is strictly contraindicated.
• It should not be used by persons under the age of 18.
• Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Tadalafil 5mg India.

Side effects and overdose

Due to the well-studied experience of Tadalafil Eli Lilly, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

• Mild headaches
• Dizziness and vomiting
• A rush of blood to the face
• Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Effect of other drugs on Tadalafil Cialis From India

Tadalafil 10mg Dosage is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Tadalafil Generic Cialis 20mg in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Tadalafil Citrate Dosage in a single dose by 107% and Smachna 15% relative to the AUC values for Tadalafil Cialis From India Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Buy Tadalafil Canada in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Tadalafil 10mg Dosage activity.

Selective inducer of CYP3A4, rifampin (600 mg/day), reduces the exposure of a single dose of Cialis Tadalafil 10mg Tablets (AUC) by 88% and SMACNA 46% relative to the AUC values for Tadalafil Tablets India Smartelco one. It can be assumed that the simultaneous use of other inducers of CYP3A4 isoenzyme should also reduce the concentration of Tadalafil Eli Lilly in plasma.

Simultaneous administration of antacid (magnesium hydroxide/aluminum hydroxide) and Buy Tadalafil Canada reduces the rate of absorption of Tadalafil Usa without changing the area under the pharmacokinetic curve for Tadalafil Eli Lilly. The increase in gastric pH as a result of the H2-histamine receptor blocker nizatidine had no effect on the pharmacokinetics of Tadalafil Dosage For Erectile Dysfunction.

The safety and effectiveness of the combination of Cialis Tadalafil 20 Mg Tablets with other types of treatment of erection disorders have not been studied, so the use of such combinations is not recommended.

Tadalafil Dosage For Erectile Dysfunction does not potentiate the increase in bleeding time caused by taking acetylsalicylic acid.

Dosage and administration

Inside. Use of Tadalafil Dosage For Erectile Dysfunction Tadalafil Usa according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Tadalafil 10mg Dosage at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Tadalafil 20 Mg Tablets. The maximum daily dose of Tadalafil For Erectile Dysfunction is 20 mg. the Use of Tadalafil Citrate Dosage according to the indication of BPH or ED/BPH. The recommended dose of Tadalafil Cialis 20mg when used once a day is 5 mg; Tadalafil 40 Mg Dosage should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Tadalafil For Erectile Dysfunction is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Cheap Generic Tadalafil at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Cheap Generic Tadalafil in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Tadalafil 40 Mg Dosage practically displayed.

Interaction with other drugs

Tadalafil Tablets India is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Cheap Generic Tadalafil. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Tadalafil Generic Cialis 20mg reduced the rate of absorption of the latter without changing the AUC. Cialis Tadalafil 20 Mg Tablets enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil Dosage For Erectile Dysfunction on the metabolism of nitric oxide and cGMP. Therefore, the use of Tadalafil Tablets India in patients receiving nitrates is contraindicated

Mechanism of action

The active substance of Cheap Generic Tadalafil is Tadalafil Usa, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Buy Tadalafil Canada.

Rules of admission

The duration of the generic Cialis Tadalafil 20 Mg Tablets reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Tadalafil Citrate Dosage should be water.

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.

To sum up: buy Cialis Tadalafil Buy Online (Tadalafil Eli Lilly) should be because

• it has a duration of 36 hours.
• virtually no side effects
• effective in diabetics
• can be combined with meals and strong drinks
• not addictive
• helps to get rid of worries about possible failure

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