Dosage and administration
Inside. Use of Tadalafil 10mg Dosage Tadalafil Dosage For Erectile Dysfunction according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Tadalafil 20 Mg Tablets at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Tadalafil Cialis From India. The maximum daily dose of Tadalafil Dosage For Erectile Dysfunction is 20 mg. the Use of Buy Cialis Tadalafil according to the indication of BPH or ED/BPH. The recommended dose of Tadalafil Tablets Usp 20 Mg when used once a day is 5 mg; Cialis Tadalafil Buy Online should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Tadalafil Tablets is contraindicated.
Side effect
Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.
Overdose
Symptoms: with a single appointment to healthy individuals Tadalafil Citrate Dosage at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Tadalafil 5mg India in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Tadalafil 40 Mg Dosage practically displayed.
Interaction with other drugs
Buy Cialis Tadalafil is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Tadalafil Cialis From India. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Tadalafil Buy Online reduced the rate of absorption of the latter without changing the AUC. Tadalafil Cialis 20mg enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil Usa on the metabolism of nitric oxide and cGMP. Therefore, the use of Tadalafil 40 Mg Dosage in patients receiving nitrates is contraindicated
Peculiar properties
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The effect on the body Buy Tadalafil Canada is similar to Viagra and similar drugs, but there are some significant differences. For example, the action of Buy Tadalafil Canada is based on the properties of Tadalafil Dosage For Erectile Dysfunction, which affects blood circulation in the pelvic organs, and the work of this substance continues for 36 hours, which is a record for today (for comparison: the duration of viagra is about 6 hours).
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Pharmacokinetics
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It is known that Cheap Generic Tadalafil increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil 10mg Dosage on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Tadalafil Cialis 20mg in patients receiving nitrates is contraindicated.
Tadalafil Cialis From India does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Tadalafil 10mg Dosage does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.
Tadalafil Eli Lilly does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Tadalafil Cialis 20mg does not affect the action of warfarin against PV.
Tadalafil Cialis From India does not increase the duration of bleeding caused by acetylsalicylic acid.
Tadalafil Tablets India has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.
In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Tadalafil 5mg India should be given appropriate clinical recommendations.
Did not observed a significant reduction in blood pressure in the application of Cialis Tadalafil Buy Online in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.
Coadministration of Tadalafil Generic Cialis 20mg with doxazosin is contraindicated. When using Tadalafil 10mg Dosage healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.
Tadalafil Tablets Usp 20 Mg did not affect the concentration of alcohol, nor did alcohol affect the concentration of Cheap Generic Tadalafil. At high doses of alcohol (0.7 g/kg), Cialis Tadalafil 20 Mg Tablets did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Tadalafil Tablets Usp 20 Mg in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.
Cheap Generic Tadalafil has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.
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