Recommendations and contraindications

Be sure to consult your doctor before taking Tadalafil Usa pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

• Like any other drug of this action, Cialis Tadalafil Tablets is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
• The body, which is sensitive to any of the components of Cialis Tadalafil 10mg Tablets, Tadalafil Tablets India is strictly contraindicated.
• It should not be used by persons under the age of 18.
• Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Tadalafil 40 Mg Dosage.

Side effects and overdose

Due to the well-studied experience of Tadalafil Tablets Usp 20 Mg, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

• Mild headaches
• Dizziness and vomiting
• A rush of blood to the face
• Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Clinical pharmacology

Several studies have been conducted to assess the effect of daily Cialis Tadalafil Buy Online on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis Tadalafil Buy Online compared to placebo.

The efficacy and safety of Cialis Tadalafil Buy Online (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Tadalafil For Erectile Dysfunction 1 time per day. In studies of the primary efficacy of Tadalafil Cialis 20mg at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Tadalafil Tablets Usp 20 Mg at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

The mechanism of action of Cialis Tadalafil 10mg Tablets in patients with BPH — inhibition of PDE-5 Tadalafil For Erectile Dysfunction, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cheap Generic Tadalafil Cheap Generic Tadalafil according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Tadalafil Tablets Usp 20 Mg at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Tadalafil Citrate Dosage. The maximum daily dose of Cialis Tadalafil Tablets is 20 mg.

The use of Tadalafil Dosage For Erectile Dysfunction Tadalafil Cialis 20mg for indication of BPH or ED/BPH.The recommended dose of Buy Cialis Tadalafil when used once a day is 5 mg; Tadalafil Generic Cialis 20mg should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Buy Cialis Tadalafil once a day is not recommended.

Effect of Cialis Tadalafil Buy Online on other drugs

It is known that Cialis Tadalafil 10mg Tablets increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil Tablets Usp 20 Mg on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Cialis Tadalafil 10mg Tablets in patients receiving nitrates is contraindicated.

Cialis Tadalafil 20 Mg Tablets does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Tadalafil 40 Mg Dosage does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Tadalafil 40 Mg Dosage does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Tadalafil Citrate Dosage does not affect the action of warfarin against PV.

Tadalafil For Erectile Dysfunction does not increase the duration of bleeding caused by acetylsalicylic acid.

Tadalafil Citrate Dosage has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Buy Cialis Tadalafil should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Tadalafil Tablets India in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Cialis Tadalafil Tablets with doxazosin is contraindicated. When using Cialis Tadalafil Tablets healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Cheap Generic Tadalafil did not affect the concentration of alcohol, nor did alcohol affect the concentration of Tadalafil Cialis 20mg. At high doses of alcohol (0.7 g/kg), Tadalafil Cialis From India did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Tadalafil Eli Lilly in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

Tadalafil 5mg India has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.

Dosage and administration

Inside. Use of Cheap Generic Tadalafil Tadalafil Tablets India according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Buy Cialis Tadalafil at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Tadalafil 10mg Dosage. The maximum daily dose of Tadalafil 5mg India is 20 mg. the Use of Tadalafil Citrate Dosage according to the indication of BPH or ED/BPH. The recommended dose of Cialis Tadalafil Tablets when used once a day is 5 mg; Tadalafil 10mg Dosage should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Tadalafil Buy Online is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Buy Tadalafil Canada at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Tadalafil For Erectile Dysfunction in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Cheap Generic Tadalafil practically displayed.

Interaction with other drugs

Tadalafil Usa is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Buy Tadalafil Canada. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Tadalafil Tablets reduced the rate of absorption of the latter without changing the AUC. Cialis Tadalafil 10mg Tablets enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil 10mg Dosage on the metabolism of nitric oxide and cGMP. Therefore, the use of Tadalafil Usa in patients receiving nitrates is contraindicated

Tadalafil Usa