Dosage and administration

Inside. Use of Cialis Tadalafil 10mg Tablets Tadalafil Tablets India according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Tadalafil Citrate Dosage at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Tadalafil Cialis From India. The maximum daily dose of Buy Tadalafil Canada is 20 mg. the Use of Tadalafil Tablets Usp 20 Mg according to the indication of BPH or ED/BPH. The recommended dose of Tadalafil Dosage For Erectile Dysfunction when used once a day is 5 mg; Cialis Tadalafil Tablets should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Tadalafil Tablets is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Tadalafil Tablets India at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Tadalafil Usa in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Tadalafil Cialis From India practically displayed.

Interaction with other drugs

Tadalafil Tablets India is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Tadalafil Eli Lilly. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Tadalafil Buy Online reduced the rate of absorption of the latter without changing the AUC. Tadalafil Tablets Usp 20 Mg enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Tadalafil Buy Online on the metabolism of nitric oxide and cGMP. Therefore, the use of Buy Cialis Tadalafil in patients receiving nitrates is contraindicated

Effect of Tadalafil Eli Lilly on other drugs

It is known that Tadalafil For Erectile Dysfunction increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Tadalafil Tablets Usp 20 Mg on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Tadalafil 10mg Dosage in patients receiving nitrates is contraindicated.

Tadalafil 10mg Dosage does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Buy Cialis Tadalafil does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Tadalafil Cialis 20mg does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Tadalafil Tablets Usp 20 Mg does not affect the action of warfarin against PV.

Tadalafil Tablets Usp 20 Mg does not increase the duration of bleeding caused by acetylsalicylic acid.

Cialis Tadalafil 10mg Tablets has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Cheap Generic Tadalafil should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Tadalafil Eli Lilly in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Tadalafil Eli Lilly with doxazosin is contraindicated. When using Tadalafil 10mg Dosage healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Cialis Tadalafil 20 Mg Tablets did not affect the concentration of alcohol, nor did alcohol affect the concentration of Tadalafil Cialis 20mg. At high doses of alcohol (0.7 g/kg), Cialis Tadalafil 20 Mg Tablets did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Cialis Tadalafil Tablets in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

Tadalafil Cialis 20mg has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.

Recommendations and contraindications

Be sure to consult your doctor before taking Tadalafil Tablets India pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

• Like any other drug of this action, Tadalafil Tablets Usp 20 Mg is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
• The body, which is sensitive to any of the components of Cheap Generic Tadalafil, Tadalafil Citrate Dosage is strictly contraindicated.
• It should not be used by persons under the age of 18.
• Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Buy Tadalafil Canada.

Side effects and overdose

Due to the well-studied experience of Cialis Tadalafil Buy Online, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

• Mild headaches
• Dizziness and vomiting
• A rush of blood to the face
• Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Mechanism of action

The active substance of Buy Cialis Tadalafil is Tadalafil Dosage For Erectile Dysfunction, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Tadalafil Tablets Usp 20 Mg.

Rules of admission

The duration of the generic Tadalafil 40 Mg Dosage reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Buy Cialis Tadalafil should be water.

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.

To sum up: buy Tadalafil For Erectile Dysfunction (Tadalafil Citrate Dosage) should be because

• it has a duration of 36 hours.
• virtually no side effects
• effective in diabetics
• can be combined with meals and strong drinks
• not addictive
• helps to get rid of worries about possible failure

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